COX By Ivan Suarez Robles 14 Nov, 2010 Abbreviation for cyclooxygenase, which is an enzyme that plays a pivotal role in the synthesis of prostaglandins.Related Articles: HD in Scrubs: My FinaleNSAIDsGlossary: COX-1Glossary: COX-2Induced Pluripotent Stem Cells: The Future of Tissue Generation