Search Results For caudate

caudate nucleus

A brain structure within the basal ganglia; responsible for regulating and organizing information being sent to the frontal lobes from other areas of the brain.

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caudate

A tail-shaped mass of neuron cell bodies. One of the components of the basal ganglia, it is involved in regulating voluntary movements. (Shortened form of caudate nucleus.)

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Impairments of Smell in Huntington’s Disease

Impairments of Smell in Huntington’s Disease
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Even before a person is diagnosed with Huntington’s Disease (HD) they may already begin experiencing symptoms. Based on recent research, the stages of HD have expanded to include pre-diagnostic stages; these are referred to as the HD prodromes.1 The Huntington’s Disease Society of America (HDSA) currently lists impairments of smell…

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Biomarkers: The Clues in us

Biomarkers: The Clues in us
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Recent research has focused on tackling the issue of the unmet medical need of an objective and quantitative biomarker for Huntington’s disease (HD). The discovery of biomarkers specific to the different stages of HD could help physicians monitor the physical changes of an individual’s HD during asymptomatic stages, and help…

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Sheep in HD Research

Sheep in HD Research
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Animal models are a crucial tool for HD research. Clinical trials invariably involve animal testing of some kind. From developing our knowledge of the immune system, to helping in the fight against cancer, animals have contributed an immeasurable wealth of knowledge to medicine. Although mouse models are currently the primary…

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HD in Without a Trace

­Episode: Second Sight Summary A young psychic named Agnes is seen flipping tarot cards as her hand trembles. Her co-worker, another psychic, notices that Agnes is in a strange mood. When she inquires about it, Agnes doesn’t divulge any information. When the co-worker leaves, Agnes flips over a card that…

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Cerebrovascular and Blood-Brain Barrier Impairments in Huntington’s Disease: Potential Implications for Its Pathophysiology

Background The brain is a complex and energy demanding organ. In order to prosper it needs a constant flow of nutrients, oxygen, and stimulation. In the developing brain for example, neuronal connections, called synapses, that are not used will eventually be pruned away, resulting in highly specific neural networks. Nutrients…

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Help 4 HD International Symposium 2014

On Friday, July 19, HOPESters Natty, Preston and Kristen made the trip down to Santa Maria, California to attend the first ever Help4HD International Symposium. The mission of Help4HD International is to facilitate conversations in the research community by providing vital information regarding research and clinical trials to the Huntington’s…

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World Congress 2013 – Basic Science Session

In September 2013, several HOPES student researchers attended the Huntington’s Disease World Congress, held in Rio de Janeiro, Brazil. Summaries of the all the sessions attended can be found in the Conferences and Conventions section of our site. The HOPES trip to the 2013 World Congress received partial support from…

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Huntington’s Disease-Like 2 (HDL2)

HDL2 Huntington’s Disease (HD) has become widely recognized by both physicians and patients alike, however, patients occasionally go to the doctor with HD symptoms and, surprisingly, genetic tests show that they do not have the HD gene mutation. These patients may have what recent investigations have unveiled as a new…

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putamen

Part of the basal ganglia in the brain. The putamen acts with the caudate to influence motor activity.

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globus pallidus

One of the components of the basal ganglia. It relays information from thecaudate and putamen to the thalamus. It is sometimes called the pallidum.

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striatum

Part of the brain that is involved in controlling movement. It is made up of the caudate and the putamen. Also referred to as the corpus striatum.

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striatal neurons

Nerve cells that make up the striatum. The striatum is a part of the brain that is involved in controlling movement. It is made up of the caudate and the putamen. Also referred to as the corpus striatum

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corpus striatum

Another term for striatum, which is a part of the brain that is involved in controlling movement. It is made up of the caudate and the putamen.

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basal ganglia

A group of nerve cells located at the base of the brain. It is composed of the putamen, caudate, globus pallidus, and substantia nigra. (The putamen and caudate together make up the striatum.) The basal ganglia participate in the regulation of motor performance, among other things. (Singular form: basal ganglion.)

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Tetrabenazine

Tetrabenazine Chorea is one of the most common and debilitating motor symptoms experienced by people with Huntington’s Disease. Tetrabenazine (TBZ) has been the drug of choice for treating chorea in 10 countries for more than a decade. However, TBZ has not been widely used in the U.S. because, until recently,…

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Meditation and HD

The practice of meditation is often viewed by Westerners as merely a form of relaxation. Many people assume that the benefits of meditation are limited to stress relief and decreased blood pressure. Brain research, however, is beginning to produce concrete evidence for something that Buddhist practitioners of meditation have believed…

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The Behavioral Symptoms of Huntington’s Disease

Behavioral-Symptoms-of-HD Huntington’s Disease (HD), an inherited neurodegenerative disease, damages specific areas of the brain, resulting in movement difficulties as well as cognitive and behavioral changes. Behavioral changes are a characteristic feature of HD and are often the most distressing aspect of the condition for individuals and families dealing with HD.…

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The Cognitive Symptoms of Huntington’s Disease

Cognitive-Symptoms-of-HD Huntington’s Disease (HD), an inherited neurodegenerative disorder, damages specific areas of the brain, resulting in movement difficulties as well as cognitive and behavioral changes. The term “cognitive” refers to tasks of the brain that involve knowing, thinking, remembering, organizing, and judging. Certain changes in cognitive abilities are characteristic of…

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